[allAfrica.com] [AED_Fundraising_Gala_Dinner_2004] Who Decisions Imperil Africa Business Day (Johannesburg) ANALYSIS October 11, 2004 Posted to the web October 11, 2004 By Roger Bate Johannesburg AID care packages for the starving and malaria-ravaged children of Sudan's wretched Darfur region "contain antimalarial medicines that will not work", Republican senator Sam Brownback said at a US hearing on malaria last week. It is astonishing that these drugs, mainly supplied by the United Nations Children's Fund (Unicef), are being included in packages when they indirectly kill children every week. Lives could easily be saved by switching to readily available alternative therapies. It is doubly disgraceful when Unicef , the World Health Organisation (WHO), the US Agency for International Development (USAid), and other agencies were criticised in January, in the medical journal The Lancet, for erroneously supplying this same medicine, chloroquine, in numerous African countries. Chloroquine has been the mainstay of anti-malaria programmes for the past 50 years, and is still useful in many countries. But in some, such as Ethiopia and Sudan, failure rates due to drug resistance reach as high as 88%, so alternatives should be used instead. Agencies' laziness, inertia, lack of attention to the scientific literature and inability to persuade African nations of the need to change drug regimes means the continued purchase of these failing drugs in Africa. More than $41m, much of it funded by US taxpayers, was spent buying these drugs for African countries in 2003. It is not yet known how much has been spent in Darfur on useless drugs, but the amount will not be trivial. These recent disasters were not the first time the WHO wasted millions of dollars on ineffective malaria interventions. In May 1995, the WHO purchased the malaria vaccine, SPf66, only to find out a year later that the incidence of malaria in the Thailand and Gambia refugee camps, where the WHO had conducted its medicine trials, had risen, proving the vaccine ineffective. Regardless of such errors, the WHO launched, with great fanfare, the Roll Back Malaria campaign in 1998, pledging to halve malaria cases by the year 2010 and demanding hundreds of millions of dollars to achieve success. Now at the halfway mark, we find that malaria cases are in fact on the rise, and that deaths have increased. While all the agencies deserve blame for the recent egregious errors, the WHO is the prime culprit. The WHO sets international health policy, behind which all aid agencies naturally coalesce . And while there is little doubt that the folks at the Geneva-based WHO mean well, their recent policies and interventions look worrisome. In the past few years, the US has provided about a quarter of the funding for the WHO. It has to be asked whether the money is well-spent. In addition to the malaria drug debacle, the WHO had to embarrassingly recall five drugs used to treat the world's biggest scourge, HIV/ AIDS. Without waiting for full safety and efficacy testing of antiretroviral drugs made by two Indian generic manufacturers, Cipla and Ranbaxy, the WHO approved the medicines for widespread use in 2001. With the WHO stamp of approval, nations started buying the cheaper copy drugs . It's too soon to know what harm has been caused, because the WHO did not carefully monitor the use of these drugs, but what is certain is that the drugs should never have left Bombay. Unfortunately, they made their way to Africa. Compounding its earlier mistake, and apparently more concerned for its own reputation than the children dying from AIDS, the WHO didn't widely announce the recall to the media. Only some weeks after its policy U-turn, when the New York Times published a story on the recall, was it widely known. Indeed, according to experts in the field, some of those who needed to know the information found out through media channels and not from the WHO. The WHO now finds itself in a ridiculous position: it has continued to promote the potentially harmful AIDS drugs because the risk of interrupting treatment is more dangerous than providing medicines whose bioequivalence is not proven. In addition to the mistakes on malaria and AIDS, there have been dubious decisions taken on measles, obesity, substitute milk products and tobacco control, to name but a few. It is time for the US congress to investigate how the money the US donates to the WHO is spent. If there is not an immediate overhaul of WHO policies, the US should withhold support, redirecting tax dollars to agencies with a better chance of success. More than a few hundred million dollars is being wasted; the lives of Africa's children, in particular, hang in the balance. Bate is a visiting fellow of the American Enterprise Institute and a Director of Africa Fighting Malaria.   =============================================================================  Copyright © 2004 Business Day. All rights reserved. Distributed by AllAfrica Global Media (allAfrica.com). =============================================================================